Copyright 2009 In Vitro Admet Laboratories I 9221 Rumsey Road Suite 8 I Columbia, MD 21045 I Tel: (410) 869-9037 Fax: (410) 869-9034 I Email: info@invitroadmet.com
SERVICES - Drug Metabolism Pathway Identification
FDA recommends the evaluation of metabolites generated by a drug for the evaluation of drug-drug interactions.
The identity of the metabolites allows the assignment of major metabolic pathways, which will facilitate experimental design for the evaluation of drug-drug interaction potential. For instance, if a drug forms phase 1 oxidation metabolites, then P450 pathways may be involved in its metabolism.
Experiments concerning P450 inhibition, induction, and P450 pathway identification are studies recommended by the FDA. We will work with you to determine the best sequence of experiments to get obtain the data you need.
Contact us for a sample protocol and pricing.
The identity of the metabolites allows the assignment of major metabolic pathways, which will facilitate experimental design for the evaluation of drug-drug interaction potential. For instance, if a drug forms phase 1 oxidation metabolites, then P450 pathways may be involved in its metabolism.
Experiments concerning P450 inhibition, induction, and P450 pathway identification are studies recommended by the FDA. We will work with you to determine the best sequence of experiments to get obtain the data you need.
Contact us for a sample protocol and pricing.
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