Copyright 2009 In Vitro Admet Laboratories I 9221 Rumsey Road Suite 8 I Columbia, MD 21045 I Tel: (410) 869-9037 Fax: (410) 869-9034 I Email: info@invitroadmet.com
SERVICES - Metabolic Stability
Metabolic stability is a key drug property which is important for both drug administration regiment design as well as toxicity. Our standard designs evaluate properties such as:
- Species comparison in metabolic stability allows the determination of which animal species is the
most appropriate model for the estimation of human metabolic stability of the test article.
- The use of liver microsomes allows the evaluation of metabolic stability as results of phase I
oxidation.
- The use of hepatocytes allows the evaluation of both phase I oxidation and phase II conjugation. We will have results for you within weeks from study initiation. Contact us to obtain a sample protocol and pricing.
- Species comparison in metabolic stability allows the determination of which animal species is the
most appropriate model for the estimation of human metabolic stability of the test article.
- The use of liver microsomes allows the evaluation of metabolic stability as results of phase I
oxidation.
- The use of hepatocytes allows the evaluation of both phase I oxidation and phase II conjugation. We will have results for you within weeks from study initiation. Contact us to obtain a sample protocol and pricing.
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